Showing posts with label phase one trial. Show all posts
Showing posts with label phase one trial. Show all posts

Friday, May 14, 2021

When one door slams shut.... another door opens!

Well that didn't take long! In less than a week I have been fortunate enough to be offered another phase 1 cancer drug trial at Princess Margaret. We are shocked and amazed really. When I went down for my scheduled appointment earlier in the week, I was not expecting to hear any positive news. I had been preparing myself for my oncologist to say that they didn't have another trial to offer at this time and that they would keep a lookout for any upcoming trials and we would be on our own until then. I thought she would offer pain medication and discuss what palliative supports were available. I am not ready for these types of discussions as I look and feel quite healthy, at least on the outside anyway. I arrived at my appointment just in time and was having a bit of deja vu as this appointment was in the same waiting room that I had been in two months previously to discuss my first trial. Here we go again! I didn't have to wait long for my oncologist to enter the room and share some exciting news.  She arrived promptly in the room and after getting Michelle on the phone for the consultation, and with very little small talk, she immediately told us that there was another clinical trial option. We were stunned and shocked really. This is not what we had expected. All week long my hopes had been dwindling and here, the door was opening up again (maybe).  

Of course this will mean that I'll be entering into a few weeks of tests and procedures and likely another biopsy - but I will gladly get poked and prodded and take this on again, with the hope of a better outcome this time around. We are currently in the process of reading over the trial information and will be coming to an informed decision as to whether or not it is a good fit for me. I have found that when your options narrow considerably, your risk tolerance goes up considerably. It will take four weeks for me to flush out from the previous trial, but I am  two weeks into that already so I should be ready to go for the end of the month. This will bring forth another set of tests and round of procedures to go through to qualify and meet the requirements of the study. I am willing to go through all the hoops required in the hope that this new trial will make a difference. 

When one door slams shut, often another door opens. I have found over my lifetime that this statement holds true. Hope is something to hold onto, despite the evidence that might suggest otherwise. Last week my hopes were dwindling and I couldn't help but feel defeated. A week later there is new hope. Just having an option, gives me hope!  This helps to reinforce that there is always hope around the corner. A new day, a new beginning. Don't get me wrong, I do understand that this new trial could eventually end up having a similar result like my last trial, having no new real impact or lasting benefit for me, however we will continue to be hopeful that it will offer some benefit, even a small benefit. At the very least it is offering us new hope and is keeping us going. We shall see how this one goes.  

A new day, a new blessing, a new hope. ~ Author Unknown

Richard 

This week is National Nurses Week! I would like to give a special shout out to all the nurses out there who work tirelessly for their patients with skill, care and compassion. Thank you! I have nothing but admiration for the work you do. By the way, I love nurses so much that I married one!  Love you Michelle.

Run for Southlake- thanks to all that supported us in this four week virtual challenge. We surpassed our goal of $2000. and ended up with $3000. in donations. We are so thankful! We also achieved our goal of 40 km over the four weeks. Thanks everyone.

Friday, March 5, 2021

Negative/Positive

Negative- Well my biopsy results finally arrived this week after some delay. After double checking the tumour samples gathered from my liver biopsy, the tumours continue to grow, and my remaining treatment options are limited. More disappointing news for me and my family. Disappointment is something that we as a family are starting to get used to. We will however, as a family, always remain hopeful and optimistic-- but I must admit that our resilience level is starting to take a big hit. I keep asking myself, why is my body doing this to me? Why can I not catch a break? I must officially and publicly declare that I hate cancer!

Positive- One thing that is for sure is that I will not let cancer take away my hope, our hope. We will continue to press on despite these limited options, despite the fact that cancer is winning at the moment. I really want to be here to experience all of the life moments with my family including future weddings, grandchildren etc. There is still so much that I want to be apart of in the lives of my children. Michelle and I have so much more  that we want to do as a couple. If  mental perspective, determination and attitude play a role, I'm drawing new battle lines.  I will not give up!

A new journey/path begins....

My next journey centres around a new drug trial at the Princess Margaret Hospital. I am in the process (again) of having final tests completed to confirm my eligibility in a existing phase one trial. If confirmed, and we have our fingers crossed, treatments would begin next week. It  is unchartered waters, but what else can we do?  I'm not liking the alternative - doing nothing.  The ball is rolling and gaining momentum. Action at least is something, right?  I've never been in a clinical trial before, so at least this will also be interesting.

This new path involves overnight stays at the hospital and intense monitoring and vigilance to watch out for any possible side effects that may occur due to the treatment.  We shall see how this all plays out. My hope is that I will once again, have minimal side effects, as was the case for my past three treatment options and that this new treatment will slow or stop my cancer in its tracks. 

Isn't there a saying something about when one window closes, another one opens?  Well here's hoping that with this negative news, we are balanced off with some positive opportunity and the trial "opens a window" for us.

So we move on to our Plan "E", and as I see it, there's many more letters where that one came from and we'll just keep cycling onward!

Richard